Job Description

Position: Research Intern in Cancer Therapeutics

Overview:

Despite significant advancements in the treatment of certain cancers, their incidence and mortality remain a major public health concern. The development of new therapeutic options is crucial to improve patient survival, especially in cases where clear therapeutic targets are lacking or conventional chemotherapies have limited efficacy and high toxicities.

Responsibilities:

• Designing classic cytotoxic agents (DNA intercalators) that are bioactivatable through a novel method currently under legal protection.
• Collaborating with a multidisciplinary team including organic synthesis of target molecules, molecular modeling to explore DNA binding modes and optimize structures, and cellular biology to study molecule-DNA interactions and anticancer effects on cell cultures.
• Conducting molecular dynamics simulations to assess the intercalation potential of targeted molecules.
• Synthesizing molecules using innovative methods.

Requirements:

• Background in molecular modeling and organic chemistry.
• Familiarity with cellular biology and cancer research.
• Strong analytical and problem-solving skills.
• Ability to work collaboratively in a research team.

Benefits:

• Gain hands-on experience in cutting-edge cancer therapeutics research.
• Opportunity to work with ONCOLille Cancer Institute on cellular biology tests.
• Contribute to the development of new therapeutic strategies for various cancer types.

Application:

Interested candidates should submit their resume and a cover letter outlining their relevant experience and interest in cancer therapeutics research.